Pathophysiology: A Practical Approach 5th Edition

Pathophysiology:  A Practical Approach, Fifth Edition provides an innovative,  practice-ready, approach to foundational pathophysiology for  pre-licensure nursing students. The text is organized by body system and  is presented in an easy-to-read format with vibrant graphics and  practice tools. Dr. Story takes a student-focused approach to the  challenging subject. She organized the content into topical chapters  that walk students through their base knowledge of A&P, what can go  wrong with the human body, how to identify it, and what to do about it.  This st-udent-friendly approach empowers readers to take a more active  role in learning pathophysiology. Students and faculty praise  Pathophysiology: A Practical Approach for its innovative presentation,  helpful Next Generation NCLEX-style questions, approachable reading  style, dynamic images, and coverage of current research.

1. Cover
2. Halftitle Page
3. The Pedagogy
4. Title Page
5. Copyright Page
6. Contents
7. Preface
8. Acknowledgments
9. Reviewers
10. Introduction to Pathophysiology
11. Chapter 1 Cellular Function
12. Basic Cell Function
13. Exchanging Material
14. Energy Production
15. Replication and Differentiation
16. Emerging Research: Stem Cells
17. Tissue
18. Epithelial Tissue
19. Connective Tissue
20. Muscle Tissue
21. Nervous Tissue
22. Cellular Adaptation and Damage
23. Cellular Adaptation
24. Cellular Injury and Death
25. Neoplasm
26. Benign and Malignant Tumors
27. Clinical Manifestations
28. Diagnosis
29. Treatment
30. Prognosis
31. Genetic and Congenital Alterations
32. Genetics
33. Patterns of Inheritance
34. Autosomal Dominant Disorders
35. Marfan Syndrome
36. Neurofibromatosis
37. Autosomal Recessive Disorders
38. Phenylketonuria
39. Clinical Manifestations
40. Sex-Linked Disorders
41. Fragile X Syndrome
42. Multifactorial Disorders
43. Cleft Lip and Cleft Palate
44. Chromosomal Disorders
45. Trisomy 21
46. Monosomy X
47. Polysomy X
48. Summary
49. References
50. Chapter 2 Immunity
51. Stress
52. The Stress Response
53. Immunity
54. Innate Versus Adaptive Immunity
55. Innate Immunity
56. Barriers
57. Inflammatory Response
58. Pyrogens
59. Interferons
60. Complement Proteins
61. Adaptive Defenses
62. Cellular Immunity
63. Humoral Immunity
64. Immunity Across the Life Span
65. Altered Immune Response
66. Hypersensitivity
67. Transplant Reactions
68. Autoimmunity
69. Systemic Lupus Erythematosus
70. Immunodeficiency
71. AIDS
72. Developing a Strong Immune System
73. Summary
74. References
75. Chapter 3 Hematopoietic Function
76. Normal Hematopoietic Function
77. Hematopoiesis
78. Hemostasis
79. Lymphatic System
80. Diseases of the White Blood Cells
81. Neutropenia
82. Infectious Mononucleosis
83. Lymphomas
84. Hodgkin’s Lymphoma
85. Non-Hodgkin’s Lymphoma
86. Leukemias
87. Multiple Myeloma
88. Diseases of the Red Blood Cells
89. Anemia
90. Iron-Deficiency Anemia
91. Pernicious Anemia
92. Aplastic Anemia
93. Hemolytic Anemia
94. Sickle Cell Anemia
95. Thalassemia
96. Polycythemia Vera
97. Diseases of the Platelets
98. Hemophilia
99. Von Willebrand Disease
100. Disseminated Intravascular Coagulation
101. Immune Thrombocytopenic Purpura
102. Thrombotic Thrombocytopenic Purpura
103. Summary
104. References
105. Chapter 4 Cardiovascular Function
106. Anatomy and Physiology
107. Heart
108. Cardiac Cycle
109. Conduction System
110. Blood Pressure
111. Blood Vessels
112. Lymphatic System
113. Understanding Conditions That Affect the Cardiovascular System
114. Alterations Resulting in Decreased Cardiac Output
115. Pericarditis
116. Infective Endocarditis
117. Myocarditis
118. Valvular Disorders
119. Cardiomyopathy
120. Electrical Alterations
121. Heart Failure
122. Congenital Heart Defects
123. Conditions Resulting in Ineffective Tissue Perfusion
124. Aneurysms
125. Dyslipidemia
126. Atherosclerosis
127. Peripheral Vascular Disease
128. Coronary Artery Disease
129. Thrombi and Emboli
130. Varicose Veins
131. Lymphedema
132. Myocardial Infarction
133. Conditions Resulting in Decreased Cardiac Output and Ineffective Tissue Perfusion
134. Hypertension
135. Shock
136. Summary
137. References
138. Chapter 5 Respiratory Function
139. Anatomy and Physiology
140. Age Considerations
141. Upper Respiratory Tract Infections
142. Infectious Rhinitis
143. Rhinosinusitis
144. Epiglottitis
145. Laryngitis
146. Laryngotracheobronchitis
147. Influenza
148. COVID-19
149. Lower Respiratory Tract Infections
150. Acute Bronchitis
151. Bronchiolitis
152. Pneumonia
153. Tuberculosis
154. Asthma
155. Chronic Obstructive Pulmonary Disease
156. Chronic Obstructive Bronchitis
157. Emphysema
158. Cystic Fibrosis
159. Lung Cancer
160. Pleural Effusion
161. Pneumothorax
162. Acute Respiratory Distress Syndrome
163. Atelectasis
164. Acute Respiratory Failure
165. Summary
166. References
167. Chapter 6 Fluid, Electrolyte, and Acid–Base Homeostasis
168. Fluid Balance
169. Distribution
170. Fluid Movement
171. Fluid Excess
172. Fluid Deficit
173. Electrolyte Balance
174. Sodium
175. Hypernatremia
176. Hyponatremia
177. Chloride
178. Hyperchloremia
179. Hypochloremia
180. Potassium
181. Hyperkalemia
182. Hypokalemia
183. Calcium
184. Hypercalcemia
185. Hypocalcemia
186. Phosphorus
187. Hyperphosphatemia
188. Hypophosphatemia
189. Magnesium
190. Hypermagnesemia
191. Hypomagnesemia
192. Acid–Base Balance
193. pH Regulation
194. Buffers
195. Respiratory Regulation
196. Renal Regulation
197. Compensation
198. Metabolic Acidosis
199. Metabolic Alkalosis
200. Respiratory Acidosis
201. Respiratory Alkalosis
202. Mixed Disorders
203. Arterial Blood Gas Interpretation
204. Practice Arterial Blood Gas Interpretation
205. Practice 1
206. Practice 2
207. Practice 3
208. Practice 4
209. Practice 5
210. Practice 6
211. Practice 7
212. Practice 8
213. Summary
214. References
215. Chapter 7 Urinary Function
216. Anatomy and Physiology
217. Conditions Resulting in Altered Urinary Elimination
218. Incontinence
219. Neurogenic Bladder
220. Interstitial Cystitis/Bladder Pain Syndrome
221. Congenital Disorders
222. Urinary Tract Infections
223. Urinary Tract Obstructions
224. Tumors and Cysts
225. Benign Prostatic Hyperplasia
226. Conditions Resulting in Impaired Renal Function
227. Polycystic Kidney Disease
228. Glomerular Diseases
229. Kidney Injury and Disease
230. Summary
231. References
232. Chapter 8 Reproductive Function
233. Anatomy and Physiology
234. Normal Male Reproductive System
235. Penis
236. Scrotum
237. Testes
238. Duct System
239. Accessory Glands
240. Normal Female Reproductive System
241. Ovaries
242. Fallopian Tubes
243. Uterus
244. Vagina
245. External Genitalia
246. Mammary Glands
247. Congenital Disorders
248. Epispadias
249. Hypospadias
250. Cryptorchidism
251. Infertility Issues
252. Erectile Dysfunction
253. Phimosis
254. Priapism
255. Disorders of the Testes and Scrotum
256. Hydrocele
257. Spermatocele
258. Varicocele
259. Testicular Torsion
260. Menstrual Disorders
261. Abnormal Uterine Bleeding
262. Amenorrhea
263. Dysmenorrhea
264. Premenstrual Syndrome
265. Pelvic Organ Prolapse
266. Vaginal Wall Prolapse
267. Uterine and Apical Prolapse
268. Disorders of the Uterus
269. Endometriosis
270. Leiomyomas
271. Disorders of the Ovaries
272. Ovarian Cysts
273. Disorders of the Breasts
274. Benign Breast Masses
275. Mastitis
276. Miscellaneous Infectious and Inflammatory Disorders
277. Prostatitis
278. Epididymitis
279. Candidiasis
280. Pelvic Inflammatory Disease
281. Sexually Transmitted Infections
282. Bacterial STIs
283. Chlamydia
284. Gonorrhea
285. Syphilis
286. Viral STIs
287. Genital Herpes
288. Condylomata Acuminata
289. Protozoan STIs
290. Trichomoniasis
291. Cancers
292. Penile Cancer
293. Prostate Cancer
294. Testicular Cancer
295. Breast Cancer
296. Cervical Cancer
297. Endometrial Cancer
298. Ovarian Cancer
299. Summary
300. References
301. Chapter 9 Gastrointestinal Function
302. Anatomy and Physiology
303. Upper Gastrointestinal Tract
304. Liver
305. Pancreas
306. Lower Gastrointestinal Tract
307. Gastrointestinal Changes Associated with Aging
308. Disorders of the Upper Gastrointestinal Tract
309. Congenital Defects
310. Dysphagia
311. Vomiting
312. Hiatal Hernia
313. Gastroesophageal Reflux Disease
314. Gastritis
315. Peptic Ulcers
316. Cholelithiasis
317. Disorders of the Liver
318. Hepatitis
319. Cirrhosis
320. Nonalcoholic Fatty Liver Disease
321. Disorders of the Pancreas
322. Pancreatitis
323. Disorders of the Lower Gastrointestinal Tract
324. Diarrhea
325. Constipation
326. Intestinal Obstruction
327. Appendicitis
328. Peritonitis
329. Celiac Disease
330. Inflammatory Bowel Disease
331. Irritable Bowel Syndrome
332. Diverticular Disease
333. Cancers
334. Oral Cancer
335. Esophageal Cancer
336. Gastric Cancer
337. Liver Cancer
338. Pancreatic Cancer
339. Colorectal Cancer
340. Summary
341. References
342. Chapter 10 Endocrine Function
343. Anatomy and Physiology
344. Hypothalamus and Pituitary Gland
345. Pancreas
346. Thyroid Gland
347. Parathyroid Glands
348. Adrenal Glands
349. Disorders of the Pituitary Gland
350. Hypopituitarism
351. Hyperpituitarism
352. Diabetes Mellitus
353. Type 1 Diabetes
354. Prediabetes
355. Type 2 Diabetes
356. Gestational Diabetes
357. Diabetes Due to Other Causes
358. Metabolic Syndrome
359. Disorders of the Thyroid
360. Goiter and Thyroid Nodules
361. Hypothyroidism
362. Hyperthyroidism
363. Disorders of the Parathyroid Glands
364. Hypoparathyroidism
365. Hyperparathyroidism
366. Disorders of the Adrenal Gland
367. Pheochromocytoma
368. Cushing Syndrome
369. Addison’s Disease
370. Summary
371. References
372. Chapter 11 Neural Function
373. Anatomy and Physiology
374. Central Nervous System
375. Peripheral Nervous System
376. Autonomic Nervous System
377. Congenital Neurologic Disorders
378. Hydrocephalus
379. Spina Bifida
380. Cerebral Palsy
381. Infectious Neurologic Disorders
382. Meningitis
383. Encephalitis
384. Zika Virus Disease
385. Traumatic Neurologic Disorders
386. Brain Injuries
387. Spinal Cord Injuries
388. Vascular Neurologic Disorders
389. Transient Ischemic Attack
390. Cerebrovascular Accident
391. Cerebral Aneurysm
392. Headache Disorders
393. Primary Headache Disorders
394. Secondary Headache Disorders
395. Seizure Disorders
396. Chronic Degenerative Disorders
397. Multiple Sclerosis
398. Parkinson’s Disease
399. Amyotrophic Lateral Sclerosis
400. Myasthenia Gravis
401. Huntington’s Disease
402. Dementia
403. Alzheimer’s Disease
404. Vascular Dementia
405. Dementia with Lewy Bodies
406. Frontotemporal Dementia
407. Creutzfeldt-Jakob Disease
408. AIDS Dementia Complex
409. Psychiatric Disorders
410. Neurodevelopmental Disorders
411. Schizophrenia Spectrum and Other Psychotic Disorders
412. Bipolar and Related Disorders
413. Depressive Disorders
414. Anxiety Disorders
415. Obsessive–Compulsive and Related Disorders
416. Trauma- and Stress-Related Disorders
417. Dissociative Disorders
418. Somatic Symptom and Related Disorders
419. Substance-Related and Addictive Disorders
420. Feeding and Eating Disorders
421. Gender Dysphoria
422. Disruptive, Impulse-Control, and Conduct Disorders
423. Personality Disorders
424. Paraphilic Disorders
425. Sleep Disorders
426. Cancers of the Nervous System
427. Brain Tumors
428. Summary
429. References
430. Chapter 12 Musculoskeletal Function
431. Anatomy and Physiology
432. Bones
433. Muscles
434. Congenital Musculoskeletal Disorders
435. Kyphosis
436. Lordosis
437. Scoliosis
438. Developmental Hip Dysplasia
439. Osteogenesis Imperfecta
440. Traumatic Musculoskeletal Disorders
441. Fractures
442. Dislocation
443. Sprains
444. Strains
445. Herniated Intervertebral Disk
446. Metabolic Bone Disorders
447. Osteoporosis
448. Rickets and Osteomalacia
449. Paget’s Disease
450. Inflammatory Joint Disorders
451. Osteoarthritis
452. Rheumatoid Arthritis
453. Gout
454. Ankylosing Spondylitis
455. Chronic Muscle Disorders
456. Muscular Dystrophy
457. Fibromyalgia
458. Bone Tumors
459. Summary
460. References
461. Chapter 13 Integumentary Function
462. Anatomy and Physiology
463. Congenital Integumentary Disorders
464. Birthmarks
465. Disorders of Melanin
466. Integumentary Changes Associated with Aging
467. Inflammatory Integumentary Disorders
468. Contact Dermatitis
469. Atopic Dermatitis
470. Urticaria
471. Psoriasis
472. Infectious Integumentary Disorders
473. Bacterial Infections
474. Viral Infections
475. Parasitic Infections
476. Traumatic Integumentary Disorders
477. Burns
478. Chronic Integumentary Disorders
479. Pressure Injuries
480. Chronic Integumentary Disorders
481. Acne Vulgaris
482. Rosacea
483. Integumentary Cancers
484. Summary
485. References
486. Chapter 14 Sensory Function
487. Anatomy and Physiology
488. Eyes
489. Ears
490. Congenital Sensory Disorders
491. Eyes
492. Ears
493. Sensory Conditions Associated with Aging
494. Eyes
495. Ears
496. Infectious and Inflammatory Sensory Disorders
497. Eyes
498. Ears
499. Traumatic Sensory Disorders
500. Eyes
501. Ears
502. Chronic Sensory Disorders
503. Eyes
504. Ears
505. Sensory Organ Cancers
506. Eyes
507. Miscellaneous Sensory Organ Conditions
508. Eyes
509. Ears
510. Summary
511. References
512. Appendix A Normal Lab Values
513. Appendix B Root Words and Combining Forms
514. Glossary
515. Index